🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧪 Experimental Design

🔬 Clinical Trials

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Trial Search

Current Search Criteria:

Intervention: E2006 Matched Placebo

Found 11 matching trials

Crossover Study to Evaluate the Effect of Lemborexant Versus Placebo and Zolpidem on Postural Stability, Auditory Awakening Threshold, and Cognitive Performance in Healthy Subjects 55 Years and Older

PHASE1

E2006-A001-108 is a 4-period crossover study designed to demonstrate that t...

Status

Completed

Location

NeuroTrials Research, Inc

Start Date

2016-11-21

Trial ID

NCT03008447

Treatments Being Tested

LEM5 LEM10 ZOL PBO

A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006

PHASE1

Part A: The purpose of this study is to evaluate the safety and tolerabilit...

Status

Completed

Location

Clinilabs, Inc.

Start Date

2011-10-05

Trial ID

NCT01463098

Treatments Being Tested

E2006 1.0 mg E2006 2.5 mg E2006 5.0 mg E2006 10.0 mg E2006 25.0 mg E2006 50.0 mg E2006 100 mg E2006 200 mg Zolpidem 10 mg E2006 Matched Placebo or Zolpidem Matched Placebo E2006 Matched Placebo

Study of Lemborexant-Alcohol Interaction in Healthy Subjects

PHASE1

This study will be conducted to evaluate the effects on cognitive performan...

Status

Completed

Location

Syneos Health

Start Date

2018-03-12

Trial ID

NCT03483636

Treatments Being Tested

Lemborexant Alcohol Placebo

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic Insomnia

PHASE2

This is a multicenter, multiple dose, randomized, double-blind, placebo-con...

Status

Completed

Location

Multiple Locations

Start Date

2013-11-13

Trial ID

NCT01995838

Treatments Being Tested

E2006 Placebo

Study of the Efficacy and Safety of Lemborexant in Subjects 55 Years and Older With Insomnia Disorder (SUNRISE 1)

PHASE3

This study will be conducted to demonstrate, using polysomnography, that le...

Status

Completed

Location

Jasper Summit Research LLC

Start Date

2016-05-31

Trial ID

NCT02783729

Treatments Being Tested

Lemborexant Lemborexant Lemborexant-matched placebo Zolpidem tartrate Zolpidem-matched placebo

2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects

PHASE1

This is a single-center, randomized, double-blind, placebo-controlled, sequ...

Status

Completed

Location

Parexel, California Clinical Trials

Start Date

2012-08

Trial ID

NCT01673451

Treatments Being Tested

E2006 Placebo comparator

A Study to Assess the Pharmacodynamics of Lemborexant in Korean Participants With Insomnia Disorder

PHASE2

The primary purpose of the study is to evaluate the treatment difference be...

Status

Completed

Location

Seoul National University Bundang Hospital

Start Date

2022-11-30

Trial ID

NCT05594589

Treatments Being Tested

Lemborexant PBO

A Two-Part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006 in Healthy Japanese and White Subjects

PHASE1

This study will be a single-center, multiple-dose, randomized, double-blind...

Status

Completed

Location

Multiple Locations

Start Date

2014-01

Trial ID

NCT02039089

Treatments Being Tested

E2006 2.5 mg E2006 10 mg E2006 25 mg Placebo

A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease

PHASE1

The primary purpose of the study is to determine whether lemborexant increa...

Status

Completed

Location

Pulmonary Associates

Start Date

2021-01-06

Trial ID

NCT04647383

Treatments Being Tested

Placebo Lemborexant 10 mg Placebo Lemborexant 10 mg

Study to Evaluate the Effect of 2 Dosage Strengths of Lemborexant (E2006) on a Multiple Sleep Latency Test in Participants With Insomnia Disorder

PHASE1

This is a single-dose, randomized, placebo-controlled, 3-way crossover stud...

Status

Completed

Location

Multiple Locations

Start Date

2014-12-13

Trial ID

NCT02350309

Treatments Being Tested

Lemborexant 5 mg Lemborexant 10 mg Lemborexant-matched placebo.Flurazepam 30 mg

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